Scientist, Immunology – Asylia Therapeutics

Asylia Therapeutics Inc., (www.asyliatx.com), is a biotech start-up founded by seasoned entrepreneurs to develop novel antibody drugs targeting the fundamental mechanisms governing immunity in cancer and autoimmune disease. Fueled by investments from a world-class investor syndicate led by Sporos Bioventures, Asylia’s platform centers on a drug pipeline capable of modulating antigen presentation to the immune system which has produced unprecedented anti-tumor responses across multiple cancer models.

In recognition of the breakthrough potential of Asylia’s technology, the company was awarded the Cancer Prevention & Research Institute of Texas (CPRIT) Seed Award for Product Development Research.

As Asylia expands upon the success of the previous year, the company is looking for additional team members to help advance development of its pipeline. This position represents unique opportunity for a highly motivated, talented, collaborative, and entrepreneurial scientist to contribute to the development of transformative therapies with the potential to impact the lives of millions.

Responsibilities:

Candidate will be a key member for the Asylia Therapeutics team, and as such would be expected to be in keeping with company values. S/he should be a self-motivated, and productive individual that can work in a fast-paced industry environment. Ability to multi-task, as well as a collaborative and cooperative positive attitude are expected of all employees. In addition, the ideal candidate will:

  • Drive the development of in vitro and in vivo immune assays to characterize the mechanism of action of antibody drug candidates
  • Have expertise in isolation and enrichment of primary cell subsets from PBMC or tumor
  • Have expertise in routine cell-based functional assays (including CTL killing assays, ADCP, ELISpot, Mixed lymphocyte reaction, etc.)
  • Be experienced in primary cell cultures, especially T-cells and monocyte lineages
  • Have experienced in other common molecular biology and other laboratory techniques including FACS, ELISA, and Immunoblot.  
  • Adhere to SOPs, and be capable of writing SOPs for novel methods
  • Design, execute, and evaluate experiments – both independently and with others
  • Assist in optimization and troubleshooting of technical challenges
  • Possess good communication skills (oral and written)
  • Participate and present at project meetings to discuss results
  • Keep organized and detailed records using an electronic laboratory notebook

Degree Qualifications:

Applicant must have a doctoral degree in immunology and post-doctoral experience in immunology or immune-oncology.

  • 3-5 years of postdoctoral training in immunology or immuno-oncology
  • PhD, in Immunology or immuno-oncology

Other Qualifications:

  • Knowledge of FcgReceptor signaling, Antigen Presenting Cell biology, MHC-I/MHC-II peptide presentation in APC, immune checkpoint signaling is a plus
  • Direct experience various enrichment kits for cell subtype isolation
  • Experience with isolation of cells from animal tumor models
  • Expertise with flow cytometry techniques, and data analysis
  • Ability to thrive in a fast-paced start-up environment
  • Ability to work both independently and collaboratively in a team environment
  • Excellent written and oral communication skills

Compensation/benefits:
Compensation is commensurate with experience
Incentive stock option, healthcare and 401k plans available

Position type:
Full-time, on-site

Location:
JLABS@TMC, Houston, Texas

Interested candidates please email Asylia_jobs@asyliatx.com